Arthrex ACP® double syringe

Trust the most researched product in the PRP / PRF industry with over 200 scientific studies.

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Fast, well tolerated, 100% endogenous substances

Liquid PRF / ACP for skin and hair

The ACP double syringe enables the production of liquid PRF / ACP in a closed system. No synthetic separating materials are used, as the liquid PRF / ACP is separated from the other blood components purely physically by centrifugation. This system, which has been successfully used and tested for many years, enables the production of a liquid PRF / ACP with an approx. 2.5-fold increase in platelet concentration with a simultaneous reduction in white blood cells and erythrocytes.1,2,3

Natural Treatment

The body's own regeneration1,6

Documented Clinical Efficacy

(+200 clinical studies / FDA-Sanctioned Level-1 Study)7

Intuitive Preparation

Fast, safe, and simple

Completely Autolog

No separating gel and no anticoagulant required

Optimized Composition2,3

Rich in fibrinogen, 2.5-fold platelet concentration, independently verified4,5

Minimal Pain During Injection1

As no anticoagulant is required

Innovative double chamber syringe

Closed system, made in Germany
In just a few minutes without the addition of foreign substances

Simple, Fast, and Safe Production

Blood sampling
Centrifugation
Aspiration
User- and patient-friendly

The Treatment Process

  1. Collection of a small amount (15 ml) of blood
  2. Extraction of the body's own active ingredients in concentrated form
  3. Injection or application of these active ingredients into/to the area to be treated
  4. Stimulation of the body's own hyaluronic acid and collagen synthesis, cell proliferation and regeneration

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PRP in Aesthetics – 10-minute Lecture on Techniques, Evidence, and Indications
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ACP/PRP Autologous Conditioned Plasma
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ACP/PRP Autologous Conditioned Plasma
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Our Products and Techniques

Arthrex ACP® double syringe

The world's leading medical product for the production of liquid PRF / ACP.
Autologous growth factors for natural beauty: simple, fast, and safe production in just a few minutes without the addition of foreign substances
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Highly concentrated PRP with autologous exosomes from platelets
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Fully automated, closed-loop production of indication-specific PRPs at the touch of a button
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References
  1. Aust M et al. Platelet-rich Plasma for Skin Rejuvenation and Treatment of Actinic Elastosis in the Lower Eyelid Area. Cureus. 2018 Jul 18;10(7):e2999.
  2. Graziani F et al. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Implants Res. 2006 Apr;17(2):212-9.
  3. Wang X et al. Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP. Int J Mol Sci. 2017 Feb 4;18(2). pii: E331.
  4. Loibl M et al. The effect of leukocyte-reduced platelet-rich plasma on the proliferation of autologous adipose-tissue derived mesenchymal stem cells. Clin Hemorheol Microcirc. 2016;61(4):599-614.
  5. Magalon J et al. Product analysis: PRP. IMCAS World Congress, Paris, France. 2017, 2018, 2019, 2020.
  6. Hetz SP et al. Patient Satisfaction and Clinical Effects of Platelet-Rich Plasma on Pattern Hair Loss in Male and Female Patients. Cureus. 2022 Sep 5;14(9):e28801.
  7. Smith PA. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016 Apr;44(4):884-91.
  8. Arthrex, Inc. data on file (APT-5368). Naples, FL; 2021.
  9. Arthrex, Inc. data on file (APT-5535). Naples, FL; 2022.
  10. Arthrex, Inc. data on file (APT-5756). Naples, FL; 2022.
  11. Torreggiani E, Perut F, Roncuzzi L, Zini N, Baglìo SR, Baldini N. Exosomes: novel effectors of human platelet lysate activity. Eur Cell Mater. 2014;28:137-151.
  12. Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles.2014;3:10.3402/jev.v3.24641.
  13. Wu J, Piao Y, Liu Q, Yang X. Platelet-rich plasma-derived extracellular vesicles: A superior alternative in regenerative medicine? Cell Prolif. 2021;54(12):e13123.
  14. Johnsen KB, Gudbergsson JM, Andresen TL, Simonsen JB. What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer. Biochim Biophys Acta Rev Cancer. 2019;1871(1):109-116.
  15. Guo SC, Tao SC, Yin WJ, Qi X, Yuan T, Zhang CQ. Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model. Theranostics. 2017;7(1):81-96.
  16. Iyer SR, Scheiber AL, Yarowsky P, Henn RF 3rd, Otsuru S, Lovering RM. Exosomes Isolated From Platelet-Rich Plasma and Mesenchymal Stem Cells Promote Recovery of Function After Muscle Injury. Am J Sports Med. 2020;48(9):2277-2286.
  17. Bai G, Truong TM, Pathak GN, Benoit L, Rao B. Clinical applications of exosomes in cosmetic dermatology. Skin Healthand Disease. Published online February 13, 2024.
  18. Anz AW et al. Quantification and Qualification of Stem Cells From Blood After Mobilization With Filgrastim, and Concentration Using a Platelet-Rich Plasma System. Arthroscopy. 2020 Nov;36(11):2911-2918
  19. Gentile P et al. Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems. Int J Mol Sci. 2017 Feb 14;18(2):408. doi: 10.3390/ijms18020408.
  20. Donovan J. Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP). JAAD Case Rep. 2015 Aug 25;1(5):305-7. doi: 10.1016/j.jdcr.2015.07.004
  21. Godek P. High Volume PRP Therapy. Ortop Traumatol Rehabil. 2022 Feb 28;24(1):43-60. doi: 10.5604/01.3001.0015.7806.
  22. Hagenau F et al. Improving morphological outcome in lamellar macular hole surgery by using highly concentrated autologous platelet-rich plasma. Graefes Arch Clin Exp Ophthalmol. 2022 May;260(5):1517-1524.
  23. Miller JD et al. Reduction of pain via platelet-rich plasma in split-thickness skin graft donor sites: a series of matched pairs.