Arthrex ACP®
Naturally Better.

Autologous Conditioned Plasma (ACP) for skin rejuvenation and treatment of alopecia

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Arthrex

Arthrex is the global market leader for PRP / PRF systems and has been distributing its high-quality medical products in various fields for more than 10 years, including aesthetic medicine, dermatology, orthopaedics and plastic surgery.
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Other innovative products and techniques, such as the ACA technique for harvesting microfat and stromal-vascular fraction (SVF) and unique training programs, help Arthrex to achieve its mission of Helping Surgeons Treat Their Patients Better®.

More than 18,000 medical devices

4 head offices and
28 subsidiaries

177 ArthroLabs in 81 countries with more than 675 workstations

More than 8,000 employees

Our Products and Techniques

Arthrex ACP® double syringe

The world's leading medical product for the production of liquid PRF / ACP.
Autologous growth factors for natural beauty: simple, fast, and safe production in just a few minutes without the addition of foreign substances
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Arthrex ACP® double syringe
Our Products and Techniques

ACP Max™ system

Highly concentrated PRP with autologous exosomes from platelets
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ACP Max™ system
Our Products and Techniques

Angel® System

Fully automated, closed-loop production of indication-specific PRPs at the touch of a button
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Angel® System
Our Products and Techniques

ACA kit

Techniques for lipofilling and concentration of the stromal-vascular fraction
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ACA kit
Our Products and Techniques

FiberWire®

The high-tech sutures for minimal foreign body reaction and anatomically long-lasting fixation.
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FiberWire®
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References
  1. Aust M et al. Platelet-rich Plasma for Skin Rejuvenation and Treatment of Actinic Elastosis in the Lower Eyelid Area. Cureus. 2018 Jul 18;10(7):e2999.
  2. Graziani F et al. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Implants Res. 2006 Apr;17(2):212-9.
  3. Wang X et al. Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP. Int J Mol Sci. 2017 Feb 4;18(2). pii: E331.
  4. Loibl M et al. The effect of leukocyte-reduced platelet-rich plasma on the proliferation of autologous adipose-tissue derived mesenchymal stem cells. Clin Hemorheol Microcirc. 2016;61(4):599-614.
  5. Magalon J et al. Product analysis: PRP. IMCAS World Congress, Paris, France. 2017, 2018, 2019, 2020.
  6. Hetz SP et al. Patient Satisfaction and Clinical Effects of Platelet-Rich Plasma on Pattern Hair Loss in Male and Female Patients. Cureus. 2022 Sep 5;14(9):e28801.
  7. Smith PA. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016 Apr;44(4):884-91.
  8. Arthrex, Inc. data on file (APT-5368). Naples, FL; 2021.
  9. Arthrex, Inc. data on file (APT-5535). Naples, FL; 2022.
  10. Arthrex, Inc. data on file (APT-5756). Naples, FL; 2022.
  11. Torreggiani E, Perut F, Roncuzzi L, Zini N, Baglìo SR, Baldini N. Exosomes: novel effectors of human platelet lysate activity. Eur Cell Mater. 2014;28:137-151.
  12. Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles.2014;3:10.3402/jev.v3.24641.
  13. Wu J, Piao Y, Liu Q, Yang X. Platelet-rich plasma-derived extracellular vesicles: A superior alternative in regenerative medicine? Cell Prolif. 2021;54(12):e13123.
  14. Johnsen KB, Gudbergsson JM, Andresen TL, Simonsen JB. What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer. Biochim Biophys Acta Rev Cancer. 2019;1871(1):109-116.
  15. Guo SC, Tao SC, Yin WJ, Qi X, Yuan T, Zhang CQ. Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model. Theranostics. 2017;7(1):81-96.
  16. Iyer SR, Scheiber AL, Yarowsky P, Henn RF 3rd, Otsuru S, Lovering RM. Exosomes Isolated From Platelet-Rich Plasma and Mesenchymal Stem Cells Promote Recovery of Function After Muscle Injury. Am J Sports Med. 2020;48(9):2277-2286.
  17. Bai G, Truong TM, Pathak GN, Benoit L, Rao B. Clinical applications of exosomes in cosmetic dermatology. Skin Healthand Disease. Published online February 13, 2024.
  18. Anz AW et al. Quantification and Qualification of Stem Cells From Blood After Mobilization With Filgrastim, and Concentration Using a Platelet-Rich Plasma System. Arthroscopy. 2020 Nov;36(11):2911-2918
  19. Gentile P et al. Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems. Int J Mol Sci. 2017 Feb 14;18(2):408. doi: 10.3390/ijms18020408.
  20. Donovan J. Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP). JAAD Case Rep. 2015 Aug 25;1(5):305-7. doi: 10.1016/j.jdcr.2015.07.004
  21. Godek P. High Volume PRP Therapy. Ortop Traumatol Rehabil. 2022 Feb 28;24(1):43-60. doi: 10.5604/01.3001.0015.7806.
  22. Hagenau F et al. Improving morphological outcome in lamellar macular hole surgery by using highly concentrated autologous platelet-rich plasma. Graefes Arch Clin Exp Ophthalmol. 2022 May;260(5):1517-1524.
  23. Miller JD et al. Reduction of pain via platelet-rich plasma in split-thickness skin graft donor sites: a series of matched pairs.